Diese Seite ist für Browser optimiert, die Web-Standards unterstützen. Andere Browser zeigen lediglich eine vereinfachte Version an, ermöglichen jedoch ebenfalls den Zugang zu allen Texten dieser Site.

Topiramate-induced persisting perception disorder Topiramate-induced persisting perception disorder
about us contact sitemap
MIGRAINE CLASSIFICATION   MIGRAINE HEADACHE   MIGRAINE AURA   MIGRAINE ART    
Printer friendly version print page
search
SYMPTOMS  |  PATHOMECHANISMS  |  HISTORY

Symptoms

Transitory aura symptoms

Persistent aura symptoms

Author: Klaus Podoll, Markus Dahlem, Sofia Greene 14. May 2008
Edited by: Klaus Podoll, Markus Dahlem, Sofia Greene

Topiramate-induced persisting perception disorder

Evans (2006) reported 2 patients aged 57 and 43, respectiely, who developed palinopsia while taking topiramate for migraine prevention which resolved or decreased in frequency or duration on lower doses, but recurred or increased in frequency or duration on higher doses. Both patients showed full remission of palinopsia when the drug was discontinued. Fontenelle (2008) observed a 35-year-old patient with psychiatric disorder who developed palinopsia (described by her as seeing of "frozen pictures" of moving objects, "picture in picture" images, like she was in a "discotheque" or in a place with stroboscopic lights, reminiscent of a variety of cinematographic vision) soon after the increase of topiramate to 100 mg/day. Although this phenomenon occurred several times during a day, it didn't bother her and she preferred not to discontinue the medication (i.e., it can be assumed that the palinopsia had a duration > 7 days in this case, although the author didn't specify its duration). In conclusion, the 3 case reports suggest that topiramate use may cause palinopsia through an unknown mechanism in both migraineurs and non-migraineurs.

References

Evans RW. Reversible palinopsia and the Alice in Wonderland syndrome associated with topiramate use in migraineurs. Headache 2006; 46: 815-818.
Fontenelle LF. Topiramate-induced palinopsia. J Neuropsychiatry Clin Neurosci 2008; 20: 249-250.

top top

MIGRAINE CLASSIFICATION  |  MIGRAINE HEADACHE  |  MIGRAINE AURA  |  MIGRAINE ART
About Us |  Contact |  IMPRINT |  Sitemap

Copyright © 2006 Migraine Aura Foundation, All rights reserved.
Thanks to: RAFFELT MEDIENDESIGN and toms-projekte.de | webmaster@migraine-aura.org

zms

http://www.migraine-aura.org/

New On Site Readers' Feedback Honors Terms Of Use Funding How can you help?

 

 

hon code
We subscribe to the HONcode principles. Verify here.

nature proceedings
Pre-publication research on migraine with aura