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Pathomechanisms
| Author: Markus Dahlem | 26. June 2005 |
| Edited by: Markus Dahlem |
Visualizing the mechanism that leads to propagation in the vascular model of migraine aura. A gradient in tolerating oxygen deprivation causes an ordered sequence of affection. © 2005 Markus Dahlem
The aura symptoms might appear as being caused by a neural traveling wave, whereas in fact a cortical gradient merely coordinates wave-like behavior. Such "phase waves" would predict a variable speed of the events spreading in the cortex. While the temporal scale should vary, the spatial path of the symptoms in sensory space, e.g. the visual field, should not vary substantially. This ist because wave-like behavior is caused by predetermined gradient in susceptibility to ischemia.
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